Merck
Scientist, Protein Characterization and Developability
South San Francisco, CA
Jan 11, 2025
Full-time
Full Job Description

Job Description

We are seeking an exceptional and enthusiastic scientist to join the Characterization and Developability group in the Discovery Biologics Protein Sciences department in South San Francisco. The successful candidate will be hands-on in the lab and they will characterize biologic modalities including antibodies, ADCs, T cell engagers, cytokine fusions, and more using a large panel of physiochemical characterization techniques including SEC, CE-SDS, HIC, nano-DSF, DSC, DLS, RP, IEX, AC-SINS, cIEF, AUC and others to support biologics drug discovery, candidate selection and optimization, quality control, and developability assessments.

We recognize that the diversity in our team is our strength and are committed to creating an inclusive environment for all employees. Successful candidates must demonstrate inclusive behaviors in working with a diverse group of scientists to drive our core mission.

What you will do:

  • Perform physiochemical characterization experiments on candidate biologics to provide recommendations for lead optimization, lead selection, and quality control

  • Analyze and interpret data

  • Provide written reports of purification and analytical data

  • Document data in an electronic lab notebook (ELN) and relevant databases

  • Present work in group and project meetings

  • Help maintain laboratory equipment

Qualifications:

Education:

  • Bachelor's (with 3 years) or Master's in Chemistry, Biochemistry, Chemical Engineering, Bioengineering, Biophysics or related field and relevant experience listed below

Required Experience and Skills:

  • Prior experience characterizing proteins

  • Ability to analyze, interpret, and effectively present data at meetings

  • General computer skills and ability to quickly learn and master computer programs, databases, and scientific applications

  • Effective organizational skills and attention to detail

  • Team player and excellent interpersonal skills

  • Effective communication skills

Preferred Experience and Skills:

  • Strong understanding of protein structure, biophysics, and analytical mindset to enable understanding of the relation between physiochemical properties and protein structure

  • Experience/interest with high-throughput analytical characterization workflows and analysis of complex datasets

  • General understanding of protein therapeutics including antibodies, multi-specifics, ADCs, and fusion proteins

Your role at our company is integral to helping the world meet new breakthroughs that affect generations to come, and we're counting on your skills and inventiveness to help make meaningful contributions to global medical advancement. At our company, we're inventing for life.

We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another's thinking and approach problems collectively for the common good. We are an equal opportunity employer, committed to fostering an inclusive and diverse workplace.

#EligibleforERP

Current Employees apply HERE

Current Contingent Workers apply HERE

US and Puerto Rico Residents Only:

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.

We are an Equal Opportunity Employer, committed to fostering an inclusive and diverse workplace. All qualified applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status, or other applicable legally protected characteristics. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

EEOC Know Your Rights

EEOC GINA Supplement

Pay Transparency Nondiscrimination

We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another's thinking and approach problems collectively.

Learn more about your rights, including under California, Colorado and other US State Acts

U.S. Hybrid Work Model

Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday - Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence.This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as "remote".

The Company is required to provide a reasonable estimate of the salary range for this job in certain states and cities within the United States. Final determinations with respect to salary will take into account a number of factors, which may include, but not be limited to the primary work location and the chosen candidate's relevant skills, experience, and education.

Expected US salary range:

$105,900.00 - $166,700.00

Available benefits include bonus eligibility, long term incentive if applicable, health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and sick days. A summary of benefits is listed here.

San Francisco Residents Only:We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

Los Angeles Residents Only:We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles' Fair Chance Initiative for Hiring Ordinance

Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

Employee Status:

Regular

Relocation:

Domestic

VISA Sponsorship:

No

Travel Requirements:

10%

Flexible Work Arrangements:

Not Applicable

Shift:

1st - Day

Valid Driving License:

No

Hazardous Material(s):

YES

Job Posting End Date:

02/28/2025

*A job posting is effective until 11:59:59PM on the day BEFOREthe listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.


Requisition ID:R330322

PDN-9df08b00-079e-4590-b497-e7dacb2fc683
Job Information
Job Category:
Science
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Scientist, Protein Characterization and Developability
Merck
South San Francisco, CA
Jan 11, 2025
Full-time
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